A proteolytic procoagulant associated with malignant transformation
نویسندگان
چکیده
منابع مشابه
Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles.
Shedding of microvesicles (MVs) by cancer cells is implicated in a variety of biological effects, including the establishment of cancer-associated hypercoagulable states. However, the mechanisms underlying malignant transformation and the acquisition of procoagulant properties by tumour-derived MVs are poorly understood. Here we investigated the procoagulant and prothrombotic properties of MVs ...
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The intramembrane organization of the plasma membranes of nonmalignant cells in culture has been compared by freeze-fracturing with that of virally-transformed malignant cells. No dramatic differences are present in the distribution of intramembrane particles in the plasma membranes of these cells when the cells are examined without fixation or with mild fixation (glutaraldehyde treatment) prio...
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OBJECTIVE To assess the frequency of hematologic malignancies at diagnosis and to determine the incidence and predictors of malignant transformation during follow-up in patients with polyneuropathy associated with monoclonal gammopathy. METHODS Potential predictors of malignant transformation from medical history, hematologic, neurologic, and laboratory examination performed each 6 months wer...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1981
ISSN: 0022-1554,1551-5044
DOI: 10.1177/29.3.457